Contradiction with James 5:15
James 5:15 speaks of the prayer of faith saving the sick and forgiving sins, implying faith's direct intervention, whereas Colossians 4:13 highlights personal effort and labor presided by Epaphras for others' wellbeing.
James 5:15: And the prayer of faith shall save the sick, and the Lord shall raise him up; and if he have committed sins, they shall be forgiven him.
Contradiction with Matthew 6:7
Matthew 6:7 warns against vain repetitions in prayer, contrasting with Colossians 4:13's focus on continuous, earnest labor in prayers for others.
Matthew 6:7: But when ye pray, use not vain repetitions, as the heathen [do]: for they think that they shall be heard for their much speaking.
Contradiction with Philippians 4:6
Philippians 4:6 promotes letting requests be made known through prayer without specific mention of labor, whereas Colossians 4:13 emphasizes Epaphras's zealous labor for others.
Philippians 4:6: Be careful for nothing; but in every thing by prayer and supplication with thanksgiving let your requests be made known unto God.
Contradiction with 1 Timothy 2:5
1 Timothy 2:5 states there is one mediator between God and men, Jesus Christ, challenging the notion in Colossians 4:13 of Epaphras's labor being pivotal for the Colossians.
1 Timothy 2:5: For [there is] one God, and one mediator between God and men, the man Christ Jesus;
Contradiction with Isaiah 55:8-9
Isaiah 55:8-9 speaks to God's ways differing from human ways, contrasting with Colossians 4:13 where human effort in prayer is emphasized.
Isaiah 55:8-9: For my thoughts [are] not your thoughts, neither [are] your ways my ways, saith the LORD.