Contradiction with Exodus 20:13
This verse commands "Thou shalt not kill," which contradicts the narrative of preparing to sacrifice Isaac.
Exodus 20:13: Thou shalt not kill.
Contradiction with Jeremiah 19:5
Mentions that God did not command burnt offerings of sons, contrasting with God asking Abraham to sacrifice Isaac.
Jeremiah 19:5: They have built also the high places of Baal, to burn their sons with fire [for] burnt offerings unto Baal, which I commanded not, nor spake [it], neither came [it] into my mind:
Contradiction with Hosea 6:6
God desires mercy, not sacrifice, opposing the act of preparing a sacrificial offering as in Genesis 22:6.
Hosea 6:6: For I desired mercy, and not sacrifice; and the knowledge of God more than burnt offerings.
Contradiction with Micah 6:7
Questions if God is pleased with human sacrifices, conflicting with Abraham carrying wood for Isaac's sacrifice.
Micah 6:7: Will the LORD be pleased with thousands of rams, [or] with ten thousands of rivers of oil? shall I give my firstborn [for] my transgression, the fruit of my body [for] the sin of my soul? [body: Heb. belly]
Contradiction with Matthew 9:13
Jesus emphasizes mercy over sacrifice, contrary to the sacrificial preparation in Genesis 22:6.
Matthew 9:13: But go ye and learn what [that] meaneth, I will have mercy, and not sacrifice: for I am not come to call the righteous, but sinners to repentance.