Contradiction with Exodus 15:3
Describes God as a man of war, which may contradict the notion of His "strange work" in Isaiah 28:21.
Exodus 15:3: The LORD [is] a man of war: the LORD [is] his name.
Contradiction with Numbers 23:19
God is not a man that He should lie, yet Isaiah 28:21 describes Him doing an unusual act.
Numbers 23:19: God [is] not a man, that he should lie; neither the son of man, that he should repent: hath he said, and shall he not do [it]? or hath he spoken, and shall he not make it good?
Contradiction with James 1:17
Every act of God is good and perfect, unlike the "strange act" mentioned in Isaiah 28:21.
James 1:17: Every good gift and every perfect gift is from above, and cometh down from the Father of lights, with whom is no variableness, neither shadow of turning.
Contradiction with 1 Corinthians 14:33
God is the author of peace, not confusion, contradicting the unfamiliarity implied in Isaiah 28:21.
1 Corinthians 14:33: For God is not [the author] of confusion, but of peace, as in all churches of the saints. [confusion: Gr. tumult, or, unquietness]
Contradiction with Malachi 3:6
God does not change, yet Isaiah 28:21 implies an unusual action from Him.
Malachi 3:6: For I [am] the LORD, I change not; therefore ye sons of Jacob are not consumed.