Contradiction with Matthew 15:24
This verse states Jesus was sent only to the lost sheep of Israel, while Isaiah 49:6 speaks of being a light to the Gentiles.
Matthew 15:24: But he answered and said, I am not sent but unto the lost sheep of the house of Israel.
Contradiction with Acts 13:46
This verse indicates that the word of God was first to be spoken to the Jews, not the Gentiles, in contrast to Isaiah 49:6’s emphasis on reaching out to the Gentiles.
Acts 13:46: Then Paul and Barnabas waxed bold, and said, It was necessary that the word of God should first have been spoken to you: but seeing ye put it from you, and judge yourselves unworthy of everlasting life, lo, we turn to the Gentiles.
Contradiction with Romans 15:8
This verse suggests Christ was a minister to the Jews to confirm promises made to the patriarchs, which appears more limited compared to Isaiah 49:6's broader mission to the Gentiles.
Romans 15:8: Now I say that Jesus Christ was a minister of the circumcision for the truth of God, to confirm the promises [made] unto the fathers: